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International Journal of Alzheimer’s Disease
Volume 2009 (2009), Article ID 689285, 7 pages
http://dx.doi.org/10.4061/2009/689285
Research Article

Amyloid Beta Annular Protofibrils in Cell Processes and Synapses Accumulate with Aging and Alzheimer-Associated Genetic Modification

1School of Health Sciences, Gunma University, 3-39-15 Showa-machi, Maebashi, Gunma 371-8514, Japan
2Geriatrics Research Institute and Hospital, 3-26-8 Ootomo-machi, Maebashi, Gunma 371-0847, Japan
3Department of Neurology, University of Texas, Medical Branch, Galveston, TX 77555, USA
4Department of Molecular Biology and Biochemistry, University of California, Irvine, Irvine, CA 92697-3900, USA
5Nervous System Department, Novartis Institutes of Biomedical Research, CH-4002 Basel, Switzerland
6Laboratory for Proteolytic Neuroscience, RIKEN Brain Science Institute, 2-1 Hirosawa, Wako-shi, Saitama 351-0198, Japan

Received 4 April 2009; Accepted 19 June 2009

Academic Editor: David Allsop

Copyright © 2009 Hideko Kokubo et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

How to Cite this Article

Hideko Kokubo, Rakez Kayed, Charles G. Glabe, et al., “Amyloid Beta Annular Protofibrils in Cell Processes and Synapses Accumulate with Aging and Alzheimer-Associated Genetic Modification,” International Journal of Alzheimer’s Disease, vol. 2009, Article ID 689285, 7 pages, 2009. doi:10.4061/2009/689285