Research Article
Gender-Specific Neuroimmunoendocrine Response to Treadmill Exercise in 3xTg-AD Mice
Table 2
Treadmill exercise recovers the [3H] flunitrazepam binding parameters of cerebral cortical tissue of 3xTgAD mice.
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Note: non-Tg, nontransgenic mice; TgSED, 3xTgAD mice not exercised; TgEXE, 3xTg-AD mice submitted to a daily treadmill running for five weeks. Exercise protected against the decrease of the affinity of [3H] flunitrazepam for its binding site in the GABA-A receptor, as showed by a low Kd. Results are the mean ± SEM, . Statistics: compared to non-Tg; compared to TgSED. |