Complex and Multidimensional Lipid Raft Alterations in a Murine Model of Alzheimer's Disease

Table 2

Receptor-specific protein list from lipid raft extracts from 3xTgAD animals. Primary protein lists of extracted lipid raft proteins were filtered for a specific receptor profile using IPA v. 8.5.

Symbol	Protein definition	Location	Protein type
Adcyap1r1	Adenylate cyclase activating polypeptide 1 (pituitary) receptor type I	Plasma membrane	G-protein coupled receptor
Cd36	CD36 molecule (thrombospondin receptor)	Plasma membrane	Transmembrane receptor
Cd86	CD86 molecule	Plasma membrane	Transmembrane receptor
Cnr1	Cannabinoid receptor 1 (brain)	Plasma membrane	G-protein coupled receptor
Cxadr	Coxsackie virus and adenovirus receptor	Plasma membrane	Transmembrane receptor
Gabbr1	Gamma-aminobutyric acid (GABA) B receptor, 1	Plasma membrane	G-protein coupled receptor
Gpr1	G protein-coupled receptor 1	Plasma membrane	G-protein coupled receptor
Gpr141	G protein-coupled receptor 141	Plasma membrane	G-protein coupled receptor
Gpr56	G protein-coupled receptor 56	Plasma membrane	G-protein coupled receptor
Htr2c	5-hydroxytryptamine (serotonin) receptor 2C	Plasma membrane	G-protein coupled receptor
Htr4	5-hydroxytryptamine (serotonin) receptor 4	Plasma membrane	G-protein coupled receptor
Igf1r	Insulin-like growth factor 1 receptor	Plasma membrane	Transmembrane receptor
Igf2r	Insulin-like growth factor 2 receptor	Plasma membrane	Transmembrane receptor
Il1r2	Interleukin 1 receptor, type II	Plasma membrane	Transmembrane receptor
Il1rapl1	Interleukin 1 receptor accessory protein-like 1	Plasma membrane	Transmembrane receptor
Lifr	Leukemia inhibitory factor receptor alpha	Plasma membrane	Transmembrane receptor
Lphn1	Latrophilin 1	Plasma membrane	G-protein coupled receptor
Lphn2	Latrophilin 2	Plasma membrane	G-protein coupled receptor
Lrpap1	Low density lipoprotein receptor-related protein associated protein 1	Plasma membrane	Transmembrane receptor
Npr2	Natriuretic peptide receptor B/guanylate cyclase B	Plasma membrane	G-protein coupled receptor
Npy5r	Neuropeptide Y receptor Y5	Plasma membrane	G-protein coupled receptor
Omg	Oligodendrocyte myelin glycoprotein	Plasma membrane	G-protein coupled receptor
Cbp	Opsin 1 (cone pigments), long-wave-sensitive	Plasma membrane	G-protein coupled receptor
Ptch1	Patched homolog 1 (Drosophila)	Plasma membrane	Transmembrane receptor
Pthr2	Parathyroid hormone 2 receptor	Plasma membrane	G-protein coupled receptor
Robo1	Roundabout, axon guidance receptor, homolog 1 (Drosophila)	Plasma membrane	Transmembrane receptor
Lgr7	Relaxin/insulin-like family peptide receptor 1	Plasma membrane	G-protein coupled receptor
Tlr5	Toll-like receptor 5	Plasma membrane	Transmembrane receptor
Tnfrsf14	Tumor necrosis factor receptor superfamily, member 14	Plasma membrane	Transmembrane receptor
Tshr	Thyroid stimulating hormone receptor	Plasma membrane	G-protein coupled receptor