TY - JOUR
A2 - Pantoni, Leonardo
AU - Chaves, Márcia L.
AU - Camozzato, Ana L.
AU - Köhler, Cristiano
AU - Kaye, Jeffrey
PY - 2010
DA - 2010/03/14
TI - Predictors of the Progression of Dementia Severity in Brazilian Patients with Alzheimer's Disease and Vascular Dementia
SP - 673581
VL - 2010
AB - Introduction. This study evaluates the progression of dementia and identifies prognostic risk factors for dementia. Methods. A group of 80 Brazilian community residents with dementia (34 with Alzheimer's disease and 46 with vascular dementia) was assessed over the course of 2 years. Data were analyzed with Cox regression survival analysis. Results. The data showed that education predicted cognitive decline (HR=1.2; P<.05) when analyzed without controlling for vascular risk factors. After the inclusion of vascular risk factors, education (HR=1.32; P<.05) and hypertension were predictive for cognitive decline (HR=38; P<.05), and Alzheimer's disease diagnosis was borderline predictive (P=.055). Conclusion. Vascular risk factors interacted with the diagnosis of vascular dementia. Education was a strong predictor of decline.
SN - 2090-8024
UR - https://doi.org/10.4061/2010/673581
DO - 10.4061/2010/673581
JF - International Journal of Alzheimer’s Disease
PB - SAGE-Hindawi Access to Research
KW -
ER -