TY - JOUR A2 - Pantoni, Leonardo AU - Chaves, Márcia L. AU - Camozzato, Ana L. AU - Köhler, Cristiano AU - Kaye, Jeffrey PY - 2010 DA - 2010/03/14 TI - Predictors of the Progression of Dementia Severity in Brazilian Patients with Alzheimer's Disease and Vascular Dementia SP - 673581 VL - 2010 AB - Introduction. This study evaluates the progression of dementia and identifies prognostic risk factors for dementia. Methods. A group of 80 Brazilian community residents with dementia (34 with Alzheimer's disease and 46 with vascular dementia) was assessed over the course of 2 years. Data were analyzed with Cox regression survival analysis. Results. The data showed that education predicted cognitive decline (HR=1.2; P<.05) when analyzed without controlling for vascular risk factors. After the inclusion of vascular risk factors, education (HR=1.32; P<.05) and hypertension were predictive for cognitive decline (HR=38; P<.05), and Alzheimer's disease diagnosis was borderline predictive (P=.055). Conclusion. Vascular risk factors interacted with the diagnosis of vascular dementia. Education was a strong predictor of decline. SN - 2090-8024 UR - https://doi.org/10.4061/2010/673581 DO - 10.4061/2010/673581 JF - International Journal of Alzheimer’s Disease PB - SAGE-Hindawi Access to Research KW - ER -