Review Article

Circadian Rhythm Disturbances in Patients with Alzheimer's Disease: A Review

Table 1

Changes in Sleep Parameters in AD.

Decrease in total sleep time
Decrease in efficiency of sleep with more fragmentation of sleep architecture
More time spent in stage 1 and stage 2 sleep and less time spent in deeper sleep
Increase in REM sleep latency and decreased REM sleep
Decreased density of eye movement activity