International Journal of Alzheimer’s Disease / 2010 / Article / Fig 1

Review Article

Neuron Loss in Transgenic Mouse Models of Alzheimer's Disease

Figure 1

Hippocampal neuron loss in the APP/PS1KI mouse model of AD. (a) APP (brown) and A staining (green) in the hippocampal formation of a 2-month-old and (c) a 10-month-old APP/PS1KI mouse. (b,d) Higher magnification of the CA1 granular cell layer of a 2-month-old (b) and a 10-month-old APP/PS1KI reveals profound neuron loss at the later time point. Scale bars: (a,c): 200  m, (b,d): 50  m.
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(a)
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