Intereleukin-10 Promoter Polymorphism in Mild Cognitive Impairment and in Its Clinical Evolution

Table 3

Distribution of genotype and allele frequencies of −1082 (G/A) SNP in MCIs that remain stable, progressed to AD (MCI→AD), and progressed to VD (MCI→VD).

	GG (H)	GA (M)	AA (L)	G	A
MCI stable	8 (28.6%)	12 (42.8%)	8 (28.6%)	28 (50%)	28 (50%)
MCI→AD	2 (8.3%)	12 (50%)	10 (41.7%)	16 (33.3%)	32 (66.7%)
MCI→VD	5 (22.7%)	11 (50%)	6 (27.3%)	21 (47.7%)	23 (52.3%)

Genotype distribution compared percentages: 𝜒² 15.604, d.f. 4; 𝑃=.004.
Allele distributions compared percentages: 𝜒² 6.661, d.f. 2; 𝑃<.05.