Chronic Cerebral Ischaemia Forms New Cholinergic Mechanisms of Learning and Memory
Figure 2
ChAT activity (top row of bars) and protein content (bottom row of bars) in the subfractions of the synaptic membranes and synaptoplasm of the light and heavy synaptosomes of the cortex and the hippocampus under 2VO conditions. Over the bars: All Rats, whole rat biochemical groups ( for control and 2VO rats); Contextual: the spatial contextual biochemical rat’s subgroup ( per group); Cued: the spatial cued biochemical rat’s subgroup ( per group). All values were expressed as percentage of enzyme activity or protein content in comparison to their control values (100%). For each pair of bars: dark bar represents synaptic membrane subfraction; light bar: synaptoplasm subfraction. CL: the subfractions of the light synaptosomal cortical fraction; CH: the subfractions of the heavy synaptosomal cortical fraction; HL: the subfractions of the light synaptosomal hippocampal fraction; HH: the subfractions of the heavy synaptosomal hippocampal fraction. *,**, significant differences from control ( and , resp.) by the Fisher’s Exact test. Comments and r-criterion values of the significant correlations by the Pearson’s test between ChAT activity and protein content or of the significant correlations between m- and c-parameters in own synaptosomal fractions see in Section 3.
