Chronic Cerebral Ischaemia Forms New Cholinergic Mechanisms of Learning and Memory
Figure 4
2VO induced changes in behavioral performance and ChAT activity in the key cholinergic populations in the spatial contextual biochemical subgroup (). 1s2, 1s3-4, 2s2–4, 3s2–4, 2s1 and 3s1, the same forms of cognition as in Figure 1. Behavioral performance was expressed as percentage of latency time compared to their control values (100%). CL, CH, HL, HH, the same pairs of the subfractions as in Figure 2. Values of ChAT activity in the subfractions are identical to ones in Figure 2-contextual, and they were duplicated under the each form of cognition. Blue bars, the values of ChAT activity had positive significant correlations with corresponding forms of cognition; violet bars, the values of ChAT activity had negative significant correlations with corresponding forms of cognition. In the middle row were marked correlations between behavioral performance and ChAT activity in the control rats (correlations correspond to Table 2, Sham-Contextual). In the bottom row were marked correlations between behavioral performance and ChAT activity in 2VO rats (correlations correspond to Table 2, 2VO—Contextual). *, by the Fisher’s exact test. See comments in Section 3.6.
