Transcranial Magnetic Stimulation Studies in Alzheimer's Disease

Figure 3

AD: Alzheimer disease, ADM: Abductor Digiti Minimi Muscle, ECD: Extensor Digitorum Communis Muscle, Hot-Spot: scalp site of maximal excitability. This picture shows that the coordinates of the map center of gravity compared to the hot-spot appear on average significantly different in the two groups: in controls the center of gravity matches with the hot spot and is located in the center of the map. In patients there is a marked frontal and medial shift of center of gravity compared to Hot-Spot. (modified from [5]).