Link between Aluminum and the Pathogenesis of Alzheimer's Disease: The Integration of the Aluminum and Amyloid Cascade Hypotheses
Figure 5
Modified aluminum hypothesis addressing the implications of Al and other trace metals in the pathogenesis of Alzheimer’s disease. This model describes the implication of Al and other trace metals including Fe, Cu, and Zn in APP processing, generation and oligomerization of AP, and the neurotoxic effects caused by AP. Details are descried in the text.
