Feasibility of Predicting MCI/AD Using Neuropsychological Tests and Serum β-Amyloid

Table 1

Variable comparisons between groups.

Variable	MCI/AD (𝑛=28)	Controls (𝑛=190)
Age	77.8±(3.9) years	76.6±(3.9) years
Education	14.61±(3.2) years	14.63±(2.8) years
% Male	67.9%	49.4%
% APOE ε 4 carrier	42.3%	32.4%
	Means ± SD
3MS	92.93±(4.0)^∗	96.7±(3.0)
MMSE	28.29±(2.1)^∗	28.98±(1.3)
HVLT-R	8.11±(2.1)^∗	9.85±(2.0)
Digit Span:
Forward Score	8.36±(2.3)	8.27±(2.0)
Backward Score	6.93±(2.1)	6.87±(1.9)
Generative Fluency	24.86±(5.8)	25.66±(6.2)
RBMT	57.14(25.4)^∗	75.00±(31.2)
BVMT-R	6.46±(2.6)^∗	8.07±(2.4)
Aβ 1–40	138.08±(43.72)	146.24±(55.37)
	Median (25th, 75th quartile)
Aβ 1–42	7.23(1.97,17.49)^∗∗	12.38(6.28,23.20)
Aβ 1–42/Aβ 1–40 ratio	0.05(0.02,0.10)^∗∗	0.09(0.05,0.15)

* t-Test 𝑃<.05.
**Mann-Whittney U 𝑃<.05.
Note: 3MS = Modified Mini-Mental State Examination; MMSE = Mini-Mental State Examination; HVLT-R = Hopkin’s Verbal Learning Test-Revised, Trial 4; RBMT = Rivermead Behavioral Memory Test; BVMT-R = Benton Visual Memory Test-Revised.