Copper Inhibits NMDA Receptor-Independent LTP and Modulates the Paired-Pulse Ratio after LTP in Mouse Hippocampal Slices
Figure 1
Electrophysiological recording in the mouse hippocampal slice. (a) In the CA1 region, the stimulating electrode (black circle) and the recording electrode (black arrow) were placed in the stratum radiatum. In the CA3 region, the mossy fibers were stimulated (white circle), and recording was done in the stratum lucidum (white arrow). (b) A representative trace from one brain slice showing how a paired-pulse test appeared at the stimulus intensity chosen for recording. (c) and (d) The average of the slopes of the fEPSPs taken 30 seconds before the tetanus was not changed by copper in either the CA1 or CA3 regions (, data not shown). Representative traces from an interleaved experiment are shown.
