Psychosis in Alzheimer's Disease in the National Alzheimer's Disease Coordinating Center Uniform Data Set: Clinical Correlates and Association with Apolipoprotein E
Table 3
Multinomial logistic regression analysis of Single and Multiple/Recurrent Psychosis.
Psychosis category
Variable
OR
95% CI
Wald ()
value
Single
Age
1.053
(1.016, 1.092)
8.083
.004
Age of onset
0.960
(0.926, 0.995)
5.047
.025
Sex
0.799
(0.633, 1.010)
3.515
.061
Race
Caucasian
0.457
(0.233, 0.898)
5.168
.023
African-American
0.834
(0.398, 1.750)
0.230
.632
Othera
Hispanic origin
0.520
(0.263, 1.029)
3.524
.061
Primary language
1.925
(0.901, 4.110)
2.862
.091
Education
0.965
(0.932, 0.999)
4.181
.041
MMSE
0.969
(0.951, 0.987)
10.924
.001
Hachinski
0.972
(0.895, 1.056)
0.437
.508
GDS
1.051
(1.007, 1.096)
5.179
.023
APOE ϵ4 allele number
0
0.778
(0.542, 1.115)
1.867
.172
1
0.815
(0.575, 1.154)
1.329
.249
2a
Multiple/Recurrent
Age
1.078
(1.034, 1.123)
12.485
<.001
Age of onset
0.914
(0.876, 0.953)
17.716
<.001
Sex
0.847
(0.631, 1.136)
1.233
.267
Race
Caucasian
0.311
(0.151, 0.642)
9.977
.002
African-American
1.008
(0.455, 2.232)
0.000
.985
Othera
Hispanic origin
0.457
(0.207, 1.007)
3.774
.052
Primary language
1.157
(0.495, 2.703)
0.113
.736
Education
0.974
(0.935, 1.014)
1.654
.198
MMSE
0.911
(0.892, 0.931)
71.322
<.001
Hachinski
1.039
(0.948, 1.140)
0.673
.412
GDS
1.077
(1.025, 1.132)
8.489
.004
APOE ϵ4 allele number
0
0.817
(0.518, 1.290)
0.751
.386
1
0.999
(0.647, 1.541)
0.000
.996
2a
Abbreviations: MMSE, Mini-mental state exam; GDS, Geriatric depression scale; APOE, Apolipoprotein E.
aReference group.
