Research Article

Thickness in Entorhinal and Subicular Cortex Predicts Episodic Memory Decline in Mild Cognitive Impairment

Figure 2

Correlation of subregional thickness in MCI subjects at their initial visit to decline in averaged score performance within cognitive domain over time. Scatterplots display: ERC thickness related to decline in Memory Encoding Domain ( ; , (a)); ERC thickness related to -change in Delayed Memory Domain ((b); not significant); Sub thickness related to decline in Memory Encoding Domain ( ; , (c)); Sub thickness related to -change in Delayed Memory Domain ((d); not significant). MCI subjects who converted to AD are highlighted in red on the Encoding Domain charts (a, c) to illustrate the relative thickness in ERC and Sub cortex compared to subjects who did not convert.
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(a) Memory encoding domain correlated to entorhinal thickness in MCI subjects
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(b) Delayed memory domain correlated to entorhinal thickness in MCI subjects
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(c) Memory encoding domain correlated to subiculum thickness in MCI subjects
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(d) Delayed memory domain correlated to subiculum thickness in MCI subjects