Cell Surface Binding and Internalization of Aβ Modulated by Degree of Aggregation
Figure 8
Intracellular localization of endocytic Aβ. Confocal microscopy images through a single plane of cells treated with either Aβ4024 or Aβ4224 and intracellular markers. All scale bars are 20 μm in length. Colocalization between the red Aβ40/4224 signal and the green lysosome signal is shown in yellow in the merged image. Colocalization was not observed with either mitochondrial or nuclear stains.