Modulation of Gamma-Secretase for the Treatment of Alzheimer's Disease

<table>Representative aryl imidazole inspired GSMs [<a href="/journals/ijad/2012/210756/#B43">30</a>–<a href="/journals/ijad/2012/210756/#B50">33</a>]. Compounds <b>16–18</b> are the most unique because the aryl imidazole has been replaced by a bioisostere [<a href="/journals/ijad/2012/210756/#B45">34</a>–<a href="/journals/ijad/2012/210756/#B47">36</a>].</table>

International Journal of Alzheimer’s Disease

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Figure 3

Figure 3: Modulation of Gamma-Secretase for the Treatment of Alzheimer's Disease 