Research Article

Centella asiatica Extract Improves Behavioral Deficits in a Mouse Model of Alzheimer's Disease: Investigation of a Possible Mechanism of Action

Table 1

Molecular weight and UV data obtained for GKW components using LC-MS and LC-UV. Reversed phase gradient HPLC chromatography with UV and negative ion mass spectral detection was performed as described in Section 2.

Retention timeMost abundant ions (m/z); (Mol Wt−1)UV max (nm)Possible structure, based on flavonoid handbook [46]

12.33 399, 353 215, 325 Prenylated flavone
16.57 531 215, 265, 310 Malonyl, butyryl, or diacetyl flavone glycoside
21.05 477 205, 255, 355 Glycosyl or glucuronyl methylated flavones
22.64 561, 515 215, 325 Diglycosyl flavonoid or a catechin
25.21 601 215, 325 No matches found
33.49 577 220, 295, 320 Diglycosyl flavonoid or a proanthocyanidin