Risk and Determinants of Dementia in Patients with Mild Cognitive Impairment and Brain Subcortical Vascular Changes: A Study of Clinical, Neuroimaging, and Biological Markers—The VMCI-Tuscany Study: Rationale, Design, and Methodology

Table 1

Instruments for patients’ assessment in the VMCI-Tuscany study protocol.

	Instruments/methods	References
Clinical assessment	Social background and medical history according to structured protocol	—
	Standard cardiovascular and neurological examination according to structured protocol	—
Motor performances	Short physical performance battery (SPPB)	[18]
	Single leg stance	[19]
	Gait velocity	[20]
Cognitive performances	Mini mental state examination (MMSE)	[21]
	Montreal cognitive assessment battery (MoCA)	[22]
	Rey auditory-verbal learning test	[23]
	Trail making test (A and B)	[24]
	Color word stroop test	[25]
	Symbol digit modalities test	[26]
	Visual search	[27]
	Phonemic and semantic fluency	[28]
	Rey-Osterrieth complex figure	[29]
	Short story recall test	[30]
Mood	Geriatric depression scale (GDS-15)	[31]
Global functioning	Activities of daily living (ADL) scale; Instrumental activities of daily living (IADL) scale	[32]; [33]