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International Journal of Alzheimer’s Disease
Volume 2012, Article ID 687909, 5 pages
http://dx.doi.org/10.1155/2012/687909
Review Article

Effect of Transcranial Brain Stimulation for the Treatment of Alzheimer Disease: A Review

1Department of Neurology, Christian Doppler Clinic, Paracelsus Medical University, 5020 Salzburg, Austria
2Department of Neurology, Franz Tappeiner Hospital, Via Rossini 5, 39012 Meran/o, Italy
3Neuroscience Institute, Christian Doppler Clinic, 5020 Salzburg, Austria
4Department of Physiology, Medical University of Graz, 8010 Graz, Austria

Received 30 July 2011; Accepted 26 August 2011

Academic Editor: Anil Nair

Copyright © 2012 Raffaele Nardone et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Linked References

  1. J. Birks, “Cholinesterase inhibitors for Alzheimer's disease,” Cochrane Database of Systematic Reviews, no. 1, Article ID CD005593, 2006. View at Google Scholar · View at Scopus
  2. A. Pascual-Leone, J. M. Tormos, J. Keenan, F. Tarazona, C. Cañete, and M. D. Catalá, “Study and modulation of human cortical excitability with transcranial magnetic stimulation,” Journal of Clinical Neurophysiology, vol. 15, no. 4, pp. 333–343, 1998. View at Google Scholar
  3. M. A. Nitsche and W. Paulus, “Excitability changes induced in the human motor cortex by weak transcranial direct current stimulation,” Journal of Physiology, vol. 527, no. 3, pp. 633–639, 2000. View at Google Scholar · View at Scopus
  4. T. Wagner, A. Valero-Cabre, and A. Pascual-Leone, “Noninvasive human brain stimulation,” Annual Review of Biomedical Engineering, vol. 9, pp. 527–565, 2007. View at Publisher · View at Google Scholar · View at Scopus
  5. J. Grafman, A. Pascual-Leone, D. Alway, P. Nichelli, E. Gomez-Tortosa, and M. Hallett, “Induction of a recall deficit by rapid-rate transcranial magnetic stimulation,” NeuroReport, vol. 5, no. 9, pp. 1157–1160, 1994. View at Google Scholar · View at Scopus
  6. B. Boroojerdi, M. Phipps, L. Kopylev, C. M. Wharton, L. G. Cohen, and J. Grafman, “Enhancing analogic reasoning with rTMS over the left prefrontal cortex,” Neurology, vol. 56, no. 4, pp. 526–528, 2001. View at Google Scholar · View at Scopus
  7. D. H. Benninger, B. D. Berman, E. Houdayer et al., “Intermittent theta-burst transcranial magnetic stimulation for treatment of Parkinson disease,” Neurology, vol. 76, no. 7, pp. 601–609, 2011. View at Publisher · View at Google Scholar
  8. E. M. Khedr and N. A. E. Fetoh, “Short- and long-term effect of rTMS on motor function recovery after ischemic stroke,” Restorative Neurology and Neuroscience, vol. 28, no. 4, pp. 545–559, 2010. View at Publisher · View at Google Scholar · View at Scopus
  9. P. Talelli and J. Rothwell, “Does brain stimulation after stroke have a future?” Current Opinion in Neurology, vol. 19, no. 6, pp. 543–550, 2006. View at Publisher · View at Google Scholar · View at Scopus
  10. A. Mantovani and S. H. Lisanby, “Applications of transcranial magnetic stimulation to therapy in psychiatry,” Psychiatr Times, vol. 21, no. 9, 2004. View at Google Scholar
  11. M. S. George, S. H. Lisanby, D. Avery et al., “Daily left prefrontal transcranial magnetic stimulation therapy for major depressive disorder: a sham-controlled randomized trial,” Archives of General Psychiatry, vol. 67, no. 5, pp. 507–516, 2010. View at Publisher · View at Google Scholar · View at Scopus
  12. C. W. Slotema, J. D. Blom, H. W. Hoek, and I. E. C. Sommer, “Should we expand the toolbox of psychiatric treatment methods to include repetitive transcranial magnetic stimulation (rTMS)? A meta-analysis of the efficacy of rTMS in psychiatric disorders,” Journal of Clinical Psychiatry, vol. 71, no. 7, pp. 873–884, 2010. View at Publisher · View at Google Scholar · View at Scopus
  13. I. Kahn, A. Pascual-Leone, H. Theoret, F. Fregni, D. Clark, and A. D. Wagner, “Transient disruption of ventrolateral prefrontal cortex during verbal encoding affects subsequent memory performance,” Journal of Neurophysiology, vol. 94, no. 1, pp. 688–698, 2005. View at Publisher · View at Google Scholar · View at Scopus
  14. M. B. Iyer, U. Mattu, J. Grafman, M. Lomarev, S. Sato, and E. M. Wassermann, “Safety and cognitive effect of frontal DC brain polarization in healthy individuals,” Neurology, vol. 64, no. 5, pp. 872–875, 2005. View at Google Scholar · View at Scopus
  15. F. Fregni, P. S. Boggio, M. Nitsche et al., “Anodal transcranial direct current stimulation of prefrontal cortex enhances working memory,” Experimental Brain Research, vol. 166, no. 1, pp. 23–30, 2005. View at Publisher · View at Google Scholar · View at Scopus
  16. W. J. Triggs, K. J. M. McCoy, R. Greer et al., “Effects of left frontal transcranial magnetic stimulation on depressed mood, cognition, and corticomotor threshold,” Biological Psychiatry, vol. 45, no. 11, pp. 1440–1446, 1999. View at Publisher · View at Google Scholar · View at Scopus
  17. F. Fregni, P. S. Boggio, M. A. Nitsche, S. P. Rigonatti, and A. Pascual-Leone, “Cognitive effects of repeated sessions of transcranial direct current stimulation in patients with depression,” Depression and Anxiety, vol. 23, no. 8, pp. 482–484, 2006. View at Publisher · View at Google Scholar · View at Scopus
  18. M. A. Nitsche, P. S. Boggio, F. Fregni, and A. Pascual-Leone, “Treatment of depression with transcranial direct current stimulation (tDCS): a review,” Experimental Neurology, vol. 219, no. 1, pp. 14–19, 2009. View at Publisher · View at Google Scholar · View at Scopus
  19. P. S. Boggio, F. Fregni, F. Bermpohl et al., “Effect of repetitive TMS and fluoxetine on cognitive function in patients with Parkinson's disease and concurrent depression,” Movement Disorders, vol. 20, no. 9, pp. 1178–1184, 2005. View at Publisher · View at Google Scholar · View at Scopus
  20. P. S. Boggio, R. Ferrucci, S. P. Rigonatti et al., “Effects of transcranial direct current stimulation on working memory in patients with Parkinson's disease,” Journal of the Neurological Sciences, vol. 249, no. 1, pp. 31–38, 2006. View at Publisher · View at Google Scholar · View at Scopus
  21. A. Monti, F. Cogiamanian, S. Marceglia et al., “Improved naming after transcranial direct current stimulation in aphasia,” Journal of Neurology, Neurosurgery and Psychiatry, vol. 79, no. 4, pp. 451–453, 2008. View at Publisher · View at Google Scholar
  22. J. M. Hoogendam, G. M. J. Ramakers, and V. Di Lazzaro, “Physiology of repetitive transcranial magnetic stimulation of the human brain,” Brain Stimulation, vol. 3, no. 2, pp. 95–118, 2010. View at Publisher · View at Google Scholar · View at Scopus
  23. C. J. Stagg and M. A. Nitsche, “Physiological basis of transcranial direct current stimulation,” Neuroscientist, vol. 17, no. 1, pp. 37–53, 2011. View at Publisher · View at Google Scholar
  24. B. Guse, P. Falkai, and T. Wobrock, “Cognitive effects of high-frequency repetitive transcranial magnetic stimulation: a systematic review,” Journal of Neural Transmission, vol. 117, no. 1, pp. 105–122, 2010. View at Publisher · View at Google Scholar · View at Scopus
  25. C. Solé-Padullés, D. Bartrés-Faz, C. Junqué et al., “Repetitive transcranial magnetic stimulation effects on brain function and cognition among elders with memory dysfunction. A randomized sham-controlled study,” Cerebral Cortex, vol. 16, no. 10, pp. 1487–1493, 2006. View at Publisher · View at Google Scholar · View at Scopus
  26. M. Cotelli, R. Manenti, S. F. Cappa et al., “Effect of transcranial magnetic stimulation on action naming in patients with Alzheimer disease,” Archives of Neurology, vol. 63, no. 11, pp. 1602–1604, 2006. View at Publisher · View at Google Scholar · View at Scopus
  27. M. Cotelli, R. Manenti, S. F. Cappa, O. Zanetti, and C. Miniussi, “Transcranial magnetic stimulation improves naming in Alzheimer disease patients at different stages of cognitive decline,” European Journal of Neurology, vol. 15, no. 12, pp. 1286–1292, 2008. View at Publisher · View at Google Scholar · View at Scopus
  28. M. Cotelli, M. Calabria, R. Manenti et al., “Improved language performance in Alzheimer disease following brain stimulation,” Journal of Neurology, Neurosurgery and Psychiatry, vol. 82, no. 7, pp. 794–797, 2011. View at Publisher · View at Google Scholar
  29. M. A. Ahmed, E. S. Darwish, E. M. Khedr, Y. M. El Serogy, and A. M. Ali, “Effects of low versus high frequencies of repetitive transcranial magnetic stimulation and functional excitability in Alzheimer’s dementia,” Journal of Neurology. In press.
  30. J. Bentwich, E. Dobronevsky, S. Aichenbaum et al., “Beneficial effect of repetitive transcranial magnetic stimulation combined with cognitive training for the treatment of Alzheimer's disease: a proof of concept study,” Journal of Neural Transmission, vol. 118, no. 3, pp. 463–471, 2011. View at Publisher · View at Google Scholar
  31. S. Rossi and P. M. Rossini, “TMS in cognitive plasticity and the potential for rehabilitation,” Trends in Cognitive Sciences, vol. 8, no. 6, pp. 273–279, 2004. View at Publisher · View at Google Scholar · View at Scopus
  32. R. Ferrucci, F. Mameli, I. Guidi et al., “Transcranial direct current stimulation improves recognition memory in Alzheimer disease,” Neurology, vol. 71, no. 7, pp. 493–498, 2008. View at Publisher · View at Google Scholar · View at Scopus
  33. P. S. Boggio, L. P. Khoury, D. C. S. Martins, O. E. M. S. Martins, E. C. de Macedo, and F. Fregni, “Temporal cortex direct current stimulation enhances performance on a Visual recognition memory task in Alzheimer disease,” Journal of Neurology, Neurosurgery and Psychiatry, vol. 80, no. 4, pp. 444–447, 2009. View at Publisher · View at Google Scholar · View at Scopus
  34. F. Rémy, F. Mirrashed, B. Campbell, and W. Richter, “Verbal episodic memory impairment in Alzheimer's disease: a combined structural and functional MRI study,” NeuroImage, vol. 25, no. 1, pp. 253–266, 2005. View at Publisher · View at Google Scholar · View at Scopus
  35. E. Scelzo, G. Giannicola, M. Rosa et al., “Increased short latency afferent inhibition after anodal transcranial direct current stimulation,” Neuroscience Letters, vol. 498, no. 2, pp. 167–170, 2011. View at Google Scholar
  36. H. Tokimura, V. Di Lazzaro, Y. Tokimura et al., “Short latency inhibition of human hand motor cortex by somatosensory input from the hand,” Journal of Physiology, vol. 523, no. 2, pp. 503–513, 2000. View at Google Scholar · View at Scopus
  37. C. Miniussi, S. F. Cappa, L. G. Cohen et al., “Efficacy of repetitive transcranial magnetic stimulation/transcranial direct current stimulation in cognitive neurorehabilitation,” Brain Stimulation, vol. 1, no. 4, pp. 326–336, 2008. View at Publisher · View at Google Scholar · View at Scopus
  38. G. Thut and C. Miniussi, “New insights into rhythmic brain activity from TMS-EEG studies,” Trends in Cognitive Sciences, vol. 13, no. 4, pp. 182–189, 2009. View at Publisher · View at Google Scholar · View at Scopus
  39. O. D. Creutzfeldt, G. H. Fromm, and H. Kapp, “Influence of transcortical d-c currents on cortical neuronal activity,” Experimental Neurology, vol. 5, no. 6, pp. 436–452, 1962. View at Google Scholar · View at Scopus
  40. C. Poreisz, K. Boros, A. Antal, and W. Paulus, “Safety aspects of transcranial direct current stimulation concerning healthy subjects and patients,” Brain Research Bulletin, vol. 72, no. 4–6, pp. 208–214, 2007. View at Publisher · View at Google Scholar · View at Scopus
  41. D. Liebetanz, M. A. Nitsche, F. Tergau, and W. Paulus, “Pharmacological approach to the mechanisms of transcranial DC-stimulation-induced after-effects of human motor cortex excitability,” Brain, vol. 125, no. 10, pp. 2238–2247, 2002. View at Google Scholar · View at Scopus
  42. G. Ardolino, B. Bossi, S. Barbieri, and A. Priori, “Non-synaptic mechanisms underlie the after-effects of cathodal transcutaneous direct current stimulation of the human brain,” Journal of Physiology, vol. 568, no. 2, pp. 653–663, 2005. View at Publisher · View at Google Scholar · View at Scopus
  43. C. Freitas, H. Mondragón-Llorca, and A. Pascual-Leone, “Noninvasive brain stimulation in Alzheimer's disease: systematic review and perspectives for the future,” Experimental Gerontology, vol. 46, no. 8, pp. 611–627, 2011. View at Publisher · View at Google Scholar
  44. J. Silvanto and A. Pascual-Leone, “State-dependency of transcranial magnetic stimulation,” Brain Topography, vol. 21, no. 1, pp. 1–10, 2008. View at Publisher · View at Google Scholar · View at Scopus