Cholesterol and Copper Affect Learning and Memory in the Rabbit

Figure 1

Photo montage of temporal lobe and hippocampus for a cholesterol-fed rabbit given distilled water supplemented with 0.12 parts per million copper as copper sulfate (right). Note the numerous dark spots that appear to be plaque-like structures that are shown in detail at bottom left. The top left image shows a thioflavin-S stained neuron from a cholesterol-fed rabbit given distilled water supplemented with 0.12 parts per million copper.