Decreased Copper in Alzheimer’s Disease Brain Is Predominantly in the Soluble Extractable Fraction

Table 3

AIBL cohort demographics for individuals analysed for erythrocyte Cu levels.

	HC	AD	𝑃 value
	(𝑁=40)	(𝑁=40)
Age (years)	76.8 (8.0)	77.3 (8.0)	>0.05
Gender females (%)	47.5	55	>0.05
ApoEε4 carriers (%)	37.5	60	<0.05
MMSE	28.4 (1.4)	18.1 (6.0)	<0.0001
CDR	0.075 (0.2)	6.175 (3.2)	<0.0001

Values are means (SD) unless noted above as otherwise. 𝑃 values were calculated using one-way ANOVA Bonferroni multiple comparison post hoc test. HC: healthy control, AD: Alzheimer's disease, and MMSE: Mini-Mental State Examination. CDR: clinical dementia rating scale, ApoEε4: Apolipoprotein E epsilon 4.