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International Journal of Alzheimer’s Disease
Volume 2014 (2014), Article ID 435202, 9 pages
http://dx.doi.org/10.1155/2014/435202
Research Article

Drug Utilization Pattern in Patients with Different Types of Dementia in Western India

1Department of Pharmacology, Ramanbhai Patel College Of Pharmacy, Charotar University of Science and Technology, Changa, Anand, Gujarat 388421, India
2Department of Pharmacology, Pramukhswami Medical College, HM Patel Centre Medical Care & Education, Gokalnagar, Karamsad, Anand, Gujarat 388325, India
3Department of Neurology, Pramukhswami Medical College, Karamsad, Anand, Gujarat 388325, India

Received 29 May 2014; Accepted 15 August 2014; Published 27 August 2014

Academic Editor: Ricardo Nitrini

Copyright © 2014 Mansi Patel et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Abstract

Background. Dementia is one of the most frequent disorders among elderly patients, reaching to epidemic proportions with an estimated 4.6 million new cases globally annually. Partially effective treatments are available for dementia. Aims & Objectives. We aim to study drugs used in dementia and find out frequency of types of Dementia. Method. This was an observational study conducted at rurally based tertiary care hospital. Prospective data was collected from outpatient department, while retrospective data was collected from medical records. Descriptive statistics were used to analyze data. Result. Total 125 prescriptions of patients diagnosed with dementia were analyzed. Alzheimer’s dementia was most common (65.6%), followed by vascular dementia (21.6%), and frontotemporal dementia (10.4%), with the rarest being Lewy body dementia in (2.4%) cases. 60.57% of patients were males. Mini Mental Score Examination mean score was 15.93 ± 1.37. Frontal Battery Assessment mean score was 4.75 ± 1.01. Prescribed drugs were Donepezil (68.49%), Rivastigmine (13.63%), Donepezil + Memantine (6.43%) and Galantamine (12.83%), Quetiapine (38.46%), Lorazepam (23.07%), Clozapine (11.53%), Escitalopram (10.25%), Haloperidol (3.84%), Zolpidem, Sertraline, Olanzepine (2.56%), Nitrazepine, Lamotrigine, Fluoxetine, Tianeptine (1.28%), Folic acid, and Vitamin B12, respectively. Conclusion. Alzheimer’s is the most common type of dementia while Donepezil was the most frequent drug.