PET Imaging of Epigenetic Influences on Alzheimer’s Disease

Figure 6

Transverse and sagittal PiB-PET scans from 2 patients with different degrees of amyloid-beta deposition. This image originates from a study examining patients with mild cognitive impairment (MCI) using positron emission tomography in combination with the radiotracer Pittsburgh compound B. It is noted that the PiB distribution volume ratio (DVR) of the patient that has progressed from MCI to AD (converter) is positive for amyloid-beta and shows a significant DVR, while the patient that is stable with MCI and has not progressed to AD (stable) is negative for Aβ and shows a lower DVR ([62], reprinted with permission).