Research Article

Inhibitory Effects of Sodium Arsenite and Acacia Honey on Acetylcholinesterase in Rats

Table 1

The activity of AChE versus the percentage (%) inhibition in the brain (cerebrum and cerebellum) and serum after Acacia honey and sodium arsenite administration in vivo.

Group TreatmentAChE activity (mole/min/g of tissue/mg protein ×10−2)% inhibition of AChE activityAChE activity (mole/min/mg protein ×102)% inhibition of AChE activity
Brain (cerebrum and cerebellum) Serum

1Distilled water533.67 ± 7.71b,c,d0.001.88 ± 0.32a,b,c0.00

220% honey302.45 ± 5.65a,c,d43.331.74 ± 0.43a7.45

35 mg/kg sodium arsenite471.55 ± 11.58a,b,d11.641.72 ± 0.19a8.51

420% honey + 5 mg/kg sodium arsenite243.76 ± 4.23a,b,c54.331.73 ± 0.54a7.98

Values are presented as mean ± SD; a: statistical significant ( < 0.05) as compared with Group 1, b: statistical significance ( < 0.05) as compared with Group 2, c: statistical significance ( < 0.05) as compared with Group 3, and d: statistical significance ( < 0.05) as compared with Group 4.