Amyloid-Beta 1-42 Cross-Reactive Antibody Prevalent in Human Sera May Contribute to Intraneuronal Deposition of A-Beta-P-42

Figure 4

Inhibition of anti-AβP-42 binding to AβP-42 , presenilin , tau protein , and BDNF coated ELISA microwells with different concentrations from 0-80 μg of the same peptides or proteins in the liquid phase. These four antigens were chosen as being representative of all the antigens that showed immune reactivity to anti-AβP-42 ranging from highly positive to very highly positive. The higher the concentration of antigens used as inhibitor, the lower the reaction of anti-AβP-42 binding to different antigens.