Impaired Cerebral Vasomotor Reactivity in Alzheimer’s Disease

Table 2

Baseline, post-CO2 test cerebral blood flow velocities, and calculated CVMR.

	Healthy Controls; (n=19)			Alzheimer’s disease; (n=26)
Velocities	Baseline; mean (±SD)	Post-CO2; mean (±SD)	Mean CVMR % (±SD)	Baseline; mean (±SD)	Post-CO2; mean (±SD)	Mean CVMR %; (±SD)
CBFV-S	69.90 (18.44)	82.64 (14.47)	21.17(17.03)	62.3619.83)	68.30(20.50)	10.88(15.26)
CBFV-D	26.36 (7.26)	31.86 (7.42)	23.29(17.48)	25.348.21)	27.09(9.78)	7.45(18.25)
CBFV-M	49.00 (15.52)	57.70 (14.08)	20.88(14.97)	38.8814.95)	43.69(16.87)	15.02(27.69)

CBFV-S: cerebral blood flow velocity-systolic; CBFV-D: cerebral blood flow velocity-diastolic; CBFV-M: cerebral blood flow velocity-mean; CVMR %: cerebral vasomotor reactivity as a percentage of change between baseline CBFV and post-CO2 test CBFV.
p < 0·05: comparison of post-CO2 mean CBFV between AD and HC groups.
p < 0.05: comparison of mean CVMR % between AD and HC groups.