Research Article
Protolichesterinic Acid: A Prominent Broad Spectrum Antimicrobial Compound from the Lichen Usnea albopunctata
Table 1
Antibacterial activity of protolichesterinic acid.
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Test bacteria | Protolichesterinic acid | Ciprofloxacin | MIC (μg/mL) | MBC (μg/mL) | Diameter of zone of inhibition (mm) | MIC (μg/mL) | MIC (μg/mL) | Diameter of zone of inhibition (mm) |
| B. subtilis | 32 | 64 | 22 | 2 | 2 | 30 | B. cereus | 64 | 64 | 21 | 1 | 2 | 31 | S. aureus | 2 | 4 | 29 | 1 | 2 | 33 | MR-S. aureus | 16 | 32 | 25 | 4 | 4 | 28 | S. epidermis | 64 | 128 | 20 | 2 | 4 | 30 | S. simulans | — | — | — | 4 | 4 | 29 | E. coli | 8 | 8 | 30 | 1 | 2 | 27 | P. mirabilis | 8 | 8 | 30 | 0.5 | 1 | 29 | P. vulgaris | 2 | 4 | 31 | 2 | 4 | 30 | V. cholerae | 0.5 | 1 | 32 | 2 | 4 | 31 | K. pneumonia | 0.25 | 0.25 | 32 | 1 | 2 | 25 | P. aeruginosa | 64 | 128 | 26 | 2 | 4 | 27 | S. typhi | 4 | 8 | 27 | 4 | 4 | 29 |
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—: no activity.
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