Table of Contents
International Journal of Antibiotics
Volume 2015 (2015), Article ID 898790, 4 pages
http://dx.doi.org/10.1155/2015/898790
Research Article

Prevalence of Multidrug Resistance among Salmonella enterica Serovar Typhimurium Isolated from Pig Faeces in Ashanti Region, Ghana

1Department of Pharmacy, Faculty of Pharmacy and Pharmaceutical Sciences, Private Mail Bag Kumasi, Kumasi, Ghana
2Department of Pharmacy, University of KwaZulu-Natal, Durban 4000, South Africa

Received 11 December 2014; Revised 15 January 2015; Accepted 16 January 2015

Academic Editor: Marilyn C. Roberts

Copyright © 2015 John Osei Sekyere and Francis Adu. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Abstract

Introduction. Salmonella typhimurium is associated with outbreaks of food-borne nontyphoidal salmonellosis (NTS) worldwide with marked multidrug resistance. Objectives. This study aimed to determine the prevalence of antibiotic resistant Salmonella typhimurium in pigs in Ashanti Region, Ghana. Methods. Faeces from 10 pigs per pig farm were collected and mixed to obtain 108 multiply-composite faecal samples. Standard microbiology and biochemical procedures were used to isolate and identify an S. typhimurium isolate from the composite faecal sample of each farm. Antibiotic sensitivity test was carried out to determine the sensitivity of the isolates. Discussion. From the 108 multiply-composite faecal samples, 72 S. typhimurium isolates were obtained from 72 separate composite samples representing 72 different pig farms. Of the 72 faecal isolates, 32 (52.8%) were resistant to at least one antibiotic. Twenty-seven isolates (71.1%) were resistant to amoxicillin and streptomycin. Resistance to tetracycline, doxycycline, and ciprofloxacin was found in 17 (44.7%), 15 (39.5%), and 8 (21.1%) isolates, respectively. Resistance to norfloxacin, sulphamethoxazole-trimethoprim, and gentamicin were expressed in 3 (7.9%), 3 (7.9%), and 0 (0.0%) isolates, respectively. Conclusion. Multiple drug resistance is common in S. typhimurium isolates, many of which could belong to the same clone, from pigs in Ashanti Region, Ghana.