International Journal of Breast Cancer / 2011 / Article / Tab 3

Research Article

A Comparative Analysis of Biomarker Expression and Molecular Subtypes of Pure Ductal Carcinoma In Situ and Invasive Breast Carcinoma by Image Analysis: Relationship of the Subtypes with Histologic Grade, Ki67, p53 Overexpression, and DNA Ploidy

Table 3

The relationship of pDCIS grade with quantitative biomarker expression.

VariablesDCIS GRADE 𝑃 value (ANOVA)

No. of casesGrade 1 (9)Grade 2 (46) Grade 3 (63)

ER score (%)89.7 ± 8.9980.9 ± 4.7858.6 ± 5.46 𝑃 = 0 . 0 0 3 7
PR score (%)62.0 ± 14.353.1 ± 5.4231.9 ± 4.69 𝑃 = 0 . 0 0 4 7
Ki67 (%)12.7 ± 2.6112.8 ± 1.3825.6 ± 2.54 𝑃 = 0 . 0 0 0 2
P53 (%)10.0 ± 5.058.83 ± 3.1121.0 ± 4.03 𝑃 = 0 . 0 0 2 9
BCL-2 (%)93.8 ± 6.2575.7 ± 5.7844.5 ± 6.78 𝑃 = 0 . 0 0 1

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