International Journal of Breast Cancer / 2011 / Article / Tab 7

Research Article

A Comparative Analysis of Biomarker Expression and Molecular Subtypes of Pure Ductal Carcinoma In Situ and Invasive Breast Carcinoma by Image Analysis: Relationship of the Subtypes with Histologic Grade, Ki67, p53 Overexpression, and DNA Ploidy

Table 7

Comparison of mean Ki67 indices in molecular subtypes of pDCIS and IBCA.

subtypesKi67Ki67  𝑃 value
DCISIBCA

LUMINAL-A6.98 Β± 0.52 ( 𝑛 = 4 4 )7.05 Β± 0.75 ( 𝑛 = 2 1 ) 𝑃 > 0 . 0 5
LUMINAL-B23.8 Β± 2.22 ( 𝑛 = 3 1 )33.76 Β± 2.53 ( 𝑛 = 3 0 ) 𝑃 > 0 . 0 5
LUM-HER223.27 Β± 2.72 ( 𝑛 = 2 2 )41.67 Β± 6.50 ( 𝑛 = 1 5 ) 𝑃 < 0 . 0 1
HER233.57 Β± 4.87 ( 𝑛 = 1 4 )58.00 Β± 9.46 ( 𝑛 = 8 ) 𝑃 < 0 . 0 1
TRIPLE NEG39.57 Β± 13.64 ( 𝑛 = 7 )67.52 Β± 6.04 ( 𝑛 = 2 6 ) 𝑃 < 0 . 0 1

* 𝑃 value calculated by two-way ANOVA followed by Bonferroni post hoc test.

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