A Role for Estrogen Receptor Phosphorylation in the Resistance to Tamoxifen

<table>Posttranslational modifications in the ER<i>α</i> hinge region. S305 phosphorylation prevents acetylation of K302/303. The natural K303R mutation blocks K302/303 acetylation and stimulates S305 phosphorylation.</table>

International Journal of Breast Cancer

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Figure 2

Figure 2: A Role for Estrogen Receptor Phosphorylation in the Resistance to Tamoxifen 