Research Article

Obesity Is an Independent Predictor of Poor Survival in Metastatic Breast Cancer: Retrospective Analysis of a Patient Cohort Whose Treatment Included High-Dose Chemotherapy and Autologous Stem Cell Support

Table 2

Independent risk factors for time from initial diagnosis to metastasis.

Years from initial diagnosis to metastasis
Median ( 𝑄 1 , 𝑄 3 )Multiple linear model*
Coefficients (95% CI) 𝑃

𝑛 Intercept : 0.87 (0.48, 1.26 )

BMI
 <30731.85 (0.97, 3.26 )Ref
 β‰₯30231.14 (0.32, 1.97 )βˆ’0.44 (βˆ’0.85, βˆ’0.02 )0.04
Stage at diagnosis
 I212.06 (1.37, 3.26 )Ref
 II432.01 (1.41, 3.29 )0.02 (βˆ’0.44, 0.48)0.92
 III230.72 (0.19, 1.94 )βˆ’0.93 (βˆ’1.46, βˆ’0.41)0.0006
 IV ( = metastasis)8N/AN/AN/A

βˆ— l o g (years from initial diagnosis to metastasis +  0.1) was used as the outcome.