International Journal of Breast Cancer

Review Article

Subgross Morphology, the Sick Lobe Hypothesis, and the Success of Breast Conservation

Table 3

Ipsilateral local recurrence rates by disease extent and type of surgery: extensive tumors defined as those occupying an area 2 cm or larger in the greatest dimension. Falun 1996–1998, 10-year followup.
Extensive tumors ≥2 cmNonextensive tumors <2 cmSumRelative riskSignificance level
Mastectomy7.7% (15/194)12.5% (2/16)8.1% (17/210) R R = 0 . 6 1 8 6
(CI: 0.1549–2.4699)		 𝑃 = . 4 9 6 5
Breast-conserving surgery12.0% (18/150)6.7% (11/163)9.3% (29/313) R R = 1 . 7 7 8 2
(CI: 0.8665–3.6407)		 𝑃 = . 1 1 5 4
Sum9.6% (33/344)7.3% (13/179)8.8% (46/523) R R = 1 . 3 2 0 9
(CI: 0.7135–2.4453)		 𝑃 = . 3 7 5 8
Relative risk R R = 1 . 5 5 2 0
(CI: 0.8082–2.9766)		 R R = 0 . 5 3 9 9
(CI: 0.1310–2.2257)		 R R = 1 . 1 4 4 5
(CI: 0.6456–2.0291)
Significance level 𝑃 = . 1 8 5 9 𝑃 = . 3 9 3 7 𝑃 = . 6 4 4 0