Subgross Morphology, the Sick Lobe Hypothesis, and the Success of Breast Conservation

Table 4

Ipsilateral local recurrence rates by disease extent and postoperative irradiation in extensive tumors and tumors of limited extent treated with breast-conserving surgery, Falun 1996–1998, 10-year followup.

Extent	Irradiated	Nonirradiated	Data missing	Sum	Relative risk	Significance level
≥4 cm	10.7% (3/28)	42.9% (6/14)	0.0% (0/2)	20.5% (9/44)	RR=4.0000; (CI: 1.1709–13.6643)	𝑃=.0270
<4 cm	3.9% (7/178)	15.2% (12/79)	50.0% (1/2)	7.4% (20/269)	RR=3.8626; (CI: 1.5803–9.2208)	𝑃=.0030