Table of Contents Author Guidelines Submit a Manuscript
International Journal of Breast Cancer
Volume 2011, Article ID 870263, 6 pages
http://dx.doi.org/10.4061/2011/870263
Research Article

Evaluation of Sentinel Node Biopsy in Locally Advanced Breast Cancer Patients Who Become Clinically Node-Negative after Neoadjuvant Chemotherapy: A Preliminary Study

1Departments of Surgery and Pathology, Lady Hardinge Medical College, Shaheed Bhagat Singh Marg, New Delhi 110001, India
2Department of Radiological Imaging, Institute of Nuclear Medicine and Allied Sciences, Delhi 110054, India

Received 18 April 2011; Revised 9 August 2011; Accepted 11 August 2011

Academic Editor: Luciane R. Cavalli

Copyright © 2011 Shaji Thomas et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Linked References

  1. R. C. Sainsbury, “The breast,” in Bailey and Love's Short Practice of Surgery, R. C. G. Russel, N. S. Williams, and C. J. S. Bulstrode, Eds., pp. 824–847, Arnold, London, UK, 24th edition, 2004. View at Google Scholar
  2. H. J. Burnstein, J. R. Harris, and M. Morrow, “Malignant tumors of the breast,” in Cancer: Principles and Practice of Oncology, V. T. Devita, T. S. Lawrence, and S. A. Rosenberg, Eds., pp. 1606–1654, Lippincott Williams & Wilkins, Philadelphia, Pa, USA, 2008. View at Google Scholar
  3. M. A. Warmuth, G. Bowen, L. R. Prosnitz et al., “Complications of axillary lymph node dissection for carcinoma of the breast: a report based on a patient survey,” Cancer, vol. 83, no. 7, pp. 1362–1368, 1998. View at Publisher · View at Google Scholar · View at Scopus
  4. F. Peintinger, R. Reitsamer, H. Stranzl, and G. Ralph, “Comparison of quality of life and arm complaints after axillary lymph node dissection vs sentinel lymph node biopsy in breast cancer patients,” British Journal of Cancer, vol. 89, no. 4, pp. 648–652, 2003. View at Publisher · View at Google Scholar · View at Scopus
  5. B. Fisher, J. Bryant, N. Wolmark et al., “Effect of preoperative chemotherapy on the outcome of women with operable breast cancer,” Journal of Clinical Oncology, vol. 16, no. 8, pp. 2672–2685, 1998. View at Google Scholar · View at Scopus
  6. J. A. Van der Hage, C. J. H. Van de Velde, J. P. Julien, M. Tubiana-Hulin, C. Vandervelden, and L. Duchateau, “Preoperative chemotherapy in primary operable breast cancer: results from the European Organization for research and treatment of cancer trial 10902,” Journal of Clinical Oncology, vol. 19, no. 22, pp. 4224–4237, 2001. View at Google Scholar · View at Scopus
  7. B. Fisher, A. Brown, E. Mamounas et al., “Effect of preoperative chemotherapy on local-regional disease in women with operable breast cancer: findings from national surgical adjuvant breast and bowel project B-18,” Journal of Clinical Oncology, vol. 15, no. 7, pp. 2483–2493, 1997. View at Google Scholar · View at Scopus
  8. H. M. Kuerer, L. A. Newman, T. L. Smith et al., “Clinical course of breast cancer patients with complete pathologic primary tumor and axillary lymph node response to doxorubicin-based neoadjuvant chemotherapy,” Journal of Clinical Oncology, vol. 17, no. 2, pp. 460–469, 1999. View at Google Scholar · View at Scopus
  9. H. M. Kuerer, A. A. Sahin, K. K. Hunt et al., “Incidence and impact of documented eradication of breast cancer axillary lymph node metastases before surgery in patients treated with neoadjuvant chemotherapy,” Annals of Surgery, vol. 230, no. 1, pp. 72–78, 1999. View at Publisher · View at Google Scholar · View at Scopus
  10. C. E. Cox, J. M. Cox, L. B. White et al., “Sentinel node biopsy before neoadjuvant chemotherapy for determining axillary status and treatment prognosis in locally advanced breast cancer,” Annals of Surgical Oncology, vol. 13, no. 4, pp. 483–490, 2006. View at Publisher · View at Google Scholar · View at Scopus
  11. NIH Consensus Conference, “Treatment of early stage breast cancer,” Journal of the American Medical Association, vol. 265, no. 3, pp. 391–395, 1991. View at Google Scholar
  12. E. C. Hsueh, N. Hansen, and A. E. Giuliano, “Intraoperative lymphatic mapping and sentinel lymph node dissection in breast cancer,” Ca-A Cancer Journal for Clinicians, vol. 50, no. 5, pp. 279–291, 2000. View at Google Scholar · View at Scopus
  13. A. E. Giuliano, P. I. Haigh, M. B. Brennan et al., “Prospective observational study of sentinel lymphadenectomy without further axillary dissection in patients with sentinel node-negative breast cancer,” Journal of Clinical Oncology, vol. 18, no. 13, pp. 2553–2559, 2000. View at Google Scholar · View at Scopus
  14. P. Schrenk, R. Rieger, A. Shamiyeh, and W. Wayand, “Morbidity following sentinel lymph node biopsy versus axillary lymph node dissection for patients with breast carcinoma,” Cancer, vol. 88, no. 3, pp. 608–614, 2000. View at Publisher · View at Google Scholar · View at Scopus
  15. A. Haid, T. Kuehn, P. Konstantiniuk et al., “Shoulder-Arm morbidity following axillary dissection and sentinel node only biopsy for breast cancer,” European Journal of Surgical Oncology, vol. 28, no. 7, pp. 705–710, 2002. View at Publisher · View at Google Scholar · View at Scopus
  16. K. K. Swenson, M. J. Nissen, C. Ceronsky, L. Swenson, M. W. Lee, and T. M. Tuttle, “Comparison of side effects between sentinel lymph node and axillary lymph node dissection for breast cancer,” Annals of Surgical Oncology, vol. 9, no. 8, pp. 745–753, 2002. View at Publisher · View at Google Scholar · View at Scopus
  17. H. S. Cody, “Clinical aspects of sentinel node biopsy,” Breast Cancer Research, vol. 3, no. 2, pp. 104–108, 2001. View at Publisher · View at Google Scholar · View at Scopus
  18. P. Schrenk, C. Tausch, S. Wölfl, S. Bogner, M. Fridrik, and W. Wayand, “Sentinel node mapping performed before preoperative chemotherapy may avoid axillary dissection in breast cancer patients with negative or micrometastatic sentinel nodes,” American Journal of Surgery, vol. 196, no. 2, pp. 176–183, 2008. View at Publisher · View at Google Scholar · View at Scopus
  19. B. J. Grube, C. J. Christy, D. Black et al., “Breast sentinel lymph node dissection before preoperative chemotherapy,” Archives of Surgery, vol. 143, no. 7, pp. 692–699, 2008. View at Publisher · View at Google Scholar · View at Scopus
  20. G. N. Hortobagyi, G. R. Blumenschein, and W. Spanos, “Multimodal treatment of locoregionally advanced breast cancer,” Cancer, vol. 51, no. 5, pp. 763–768, 1983. View at Google Scholar · View at Scopus
  21. M. E. Lippman, R. A. Sorace, and C. S. Bagley, “Treatment of locally advanced breast cancer using primary induction chemotherapy with hormonal synchronization followed by radiation therapy with or without debulking surgery,” NCI Monographs, vol. 1, pp. 153–159, 1986. View at Google Scholar · View at Scopus
  22. E. P. Mamounas, “Overview of national surgical adjuvant breast project neoadjuvant chemotherapy studies,” Seminars in Oncology, vol. 25, no. 2, pp. 31–35, 1998. View at Google Scholar · View at Scopus
  23. S. E. Singletary, M. D. McNeese, and G. N. Hortobagyi, “Feasibility of breast-conservation surgery after induction chemotherapy for locally advanced breast carcinoma,” Cancer, vol. 69, no. 11, pp. 2849–2852, 1992. View at Publisher · View at Google Scholar · View at Scopus
  24. G. F. Schwartz, C. A. Birchansky, L. T. Komarnicky et al., “Induction chemotherapy followed by breast conservation for locally advanced carcinoma of the breast,” Cancer, vol. 73, no. 2, pp. 362–369, 1994. View at Google Scholar · View at Scopus
  25. G. Bonadonna, P. Valagussa, C. Brambilla et al., “Primary chemotherapy in operable breast cancer: eight-year experience at the Milan Cancer Institute,” Journal of Clinical Oncology, vol. 16, no. 1, pp. 93–100, 1998. View at Google Scholar · View at Scopus
  26. E. P. Mamounas, “Sentinel lymph node biopsy after neoadjuvant systemic therapy,” Surgical Clinics of North America, vol. 83, no. 4, pp. 931–942, 2003. View at Google Scholar · View at Scopus
  27. Y. Xing, M. Foy, D. D. Cox, H. M. Kuerer, K. K. Hunt, and J. N. Cormier, “Meta-analysis of sentinel lymph node biopsy after preoperative chemotherapy in patients with breast cancer,” British Journal of Surgery, vol. 93, no. 5, pp. 539–546, 2006. View at Publisher · View at Google Scholar
  28. National Cancer Institute at the National Institutes of Health, september 2011, http://www.cancer.gov/clinicaltrials/search/view?cdrid=640100&version=healthprofessional#EntryCriteria_CDR0000640100.
  29. J. Shen, M. Z. Gilcrease, G. V. Babiera et al., “Feasibility and accuracy of sentinel lymph node biopsy after preoperative chemotherapy in breast cancer patients with documented axillary metastases,” Cancer, vol. 109, no. 7, pp. 1255–1263, 2007. View at Publisher · View at Google Scholar · View at Scopus
  30. E. A. Newman, M. S. Sabel, A. V. Nees et al., “Sentinel lymph node biopsy performed after neoadjuvant chemotherapy is accurate in patients with documented node-positive breast cancer at presentation,” Annals of Surgical Oncology, vol. 14, no. 10, pp. 2946–2952, 2007. View at Publisher · View at Google Scholar · View at Scopus
  31. S. Lee, E. Y. Kim, S. H. Kang et al., “Sentinel node identification rate, but not accuracy, is significantly decreased after pre-operative chemotherapy in axillary node-positive breast cancer patients,” Breast Cancer Research and Treatment, vol. 102, no. 3, pp. 283–288, 2007. View at Publisher · View at Google Scholar · View at Scopus