Prognostic Significance of Tissue Inhibitor of Metalloproteinase-1 in Breast Cancer

Table 3

Multivariate analysis for recurrence-free survival using TIMP-1 mRNA levels.

Parameter	Hazard ratio	95% CI	𝑃 value
TIMP-1 mRNA levels	1.68	1.02–2.78	0.04
ER status	1.32	0.81–2.15	0.27
HER2 status	0.90	0.50–1.59	0.71
Stage	0.95	0.55–1.63	0.84
Grade	1.56	0.91–2.68	0.11