Prognostic Significance of Tissue Inhibitor of Metalloproteinase-1 in Breast Cancer

Table 5

Occurrence of clinical/pathological features in patients with high levels of TIMP-1 protein (𝑛=94) compared to patients with low levels of TIMP-1 protein (𝑛=51).

Cytoplasmic TIMP-1 score	High (3+)	Low (0, 1+, 2+)	𝑃
Total	94	51
Recurrence	49	29	0.59
Death	41	20	0.61
Negative ER status	40	15	0.12
High grade	71	32	0.11
HER2 amplified	18	7	0.36
Stage I	18	13
Stage IIA/IIB	66	36	0.30
Stage IIIA/IIIB	10	2