Comparison of the Subgross Distribution of the Lesions in Invasive Ductal and Lobular Carcinomas of the Breast: A Large-Format Histology Study
Table 2
Proportion of cases with lymph node metastases in ductal and lobular carcinomas by lesion distribution and disease extent, Dalarna, Jan 2008–Jul 2012.
Ductal
Lobular
Comparison of proportions
Invasive component
Unifocal
27.5% (102/371)
18.9% (7/37)
(−35.3%–29.4%)
Multifocal
53.8% (112/208)
34.4% (21/61)
(−5.5%–41.2%)
Diffuse
85.7% (6/7)
48.6% (17/35)
(−16.7%–65.1%)
Lesion distribution
In situ* component
Unifocal
33.1% (83/251)
16.0% (4/25)
(−42.2%–36.5%)
Multifocal
43.5% (64/147)
40.2% (37/92)
(−17.3%–24.4%)
Diffuse
43.3% (68/157)
33.3% (3/9)
(−48.7%–44.6%)
Combined in situ + invasive components
Unifocal
29.9% (73/244)
20.0% (4/20)
(−48.1%–33.1%)
Multifocal
42.2% (78/185)
31.9% (23/72)
(−15.1%–31.2%)
Diffuse
43.9% (69/157)
43.9% (18/41)
(−26.0%–27.6%)
Disease extent**
Nonextensive
27.1% (86/317)
26.7% (12/45)
(−23.1%–33.4%)
Extensive
50.0% (134/268)
37.9% (33/87)
(−8.5%–30.5%)
Total
586
133
*5.3% (31/586) of the ductal and 5.2% (7/133) of the lobular cases had no demonstrable in situ component.
**The extent of the disease was not assessable in 0.2% (1/586) of the ductal and 0.8% (1/133) of the lobular cancers.
