International Journal of Breast Cancer / 2012 / Article / Fig 4

Research Article

Preclinical Evaluation of Oncolytic Δγ134.5 Herpes Simplex Virus Expressing Interleukin-12 for Therapy of Breast Cancer Brain Metastases

Figure 4

Cytotoxicity of M002 in human and murine tumor cells at 48 h post-infection. Plates of human breast cancer cells MDA-MB-361 (a) or murine mammary carcinoma cells SCK (b), and 4T1 (c) were infected with the indicated viruses at an MOI of 1 (black bars) or 10 (gray bars) PFU/cell. At 48 h post-infection, cell viability was assayed by MTT assay. Shown are the averages of quadruplicate determinations, normalized to uninfected cells and expressed as the proportion viable cells.
628697.fig.004a
(a)
628697.fig.004b
(b)
628697.fig.004c
(c)

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