Effect of Melatonin on Cognitive Function and Sleep in relation to Breast Cancer Surgery: A Randomized, Double-Blind, Placebo-Controlled Trial

Table 3

The 7 variables of the 4 neuropsychological tests.

	Baseline; MEL	Baseline; PLC	Test 1; MEL	Test 1; PLC	Test 2; MEL	Test 2; PLC
Visual Verbal Learning, cumulated recall	30 (25–33)	27 (25–30)	31 (27–33.25)	30 (27–31.75)	32.5 (29–37.25)	28.5 (23.25–30)
Visual Verbal Learning, delayed recall	11 (9–13)	10 (7.5–11)	11 (10–13.25)	11 (8–12)	11 (9.75–12.25)	9 (8–10)
Concept Shifting Test, time	27.34 (22.62–34.87)	32.91 (28.11–39.51)	26.25 (22.85–34.13)	33.5 (27.17–36.29)	32.16 (23.06–37.78)	30.86 (27.51–38.29)
Concept Shifting, error score	0 (0-0)	0 (0-0)	0 (0-0)	0 (0-0)	0 (0-0)	0 (0-0)
Stroop Color-Word Interference, time	40.20 (33.16–46.93)	44.41 (39.95–52.75)	36.37 (28.53–43.47)	39.96 (34.81–43.69)	35.41 (29.88–43.00)	38.40 (33.49–45.63)
Stroop Color-Word Interference, error score	0 (0-0)	0 (0–0.5)	0 (0-0)	0 (0-0)	0 (0-0)	0 (0–0.75)
Letter-Digit Coding	35 (29.5–38.75)	33 (29–37)	38 (33–40)	36 (30.75–38.75)	36 (22–41)	39 (35–41)

Values are median (IQR).
Data are presented as number of words, time in seconds/milliseconds, or number of errors.
MEL: melatonin, PLC: placebo.