Research Article

Associations between Reoperations and Psychological Factors after Contralateral Risk-Reducing Mastectomy: A Two-Year Follow-Up Study

Table 1

Demographic and clinical data for all eligible patients according to reoperation after CRRM ().

VariableNo reoperation
(%)
Reoperation
(%)
value

Age at CPM, years
 25–355 (13.9)7 (15.9)0.85
 35–4513 (36.1)19 (43.2)
 45–5511 (30.6)12 (27.3)
 55–657 (19.4)6 (13.7)
BRCA mutation status
 BRCA116 (44.4)18 (40.9)0.14
BRCA27 (19.5)2 (4.6)
BRCAX9 (25.0)17 (38.6)
 No mutation or unknown4 (11.1)7 (15.9)
Prophylactic salpingo-oophorectomy
 Yes20 (55.6)16 (36.4)0.09
 No16 (44.4)28 (63.6)
Primary tumor size
 Tis 4 (11.1)2 (4.6)0.61
 T118 (50.0)25 (56.8)
 T210 (27.8)14 (31.8)
 T34 (11.1) 3 (6.8)
Lymph nodes
 N+18 (50.0)23 (52.3)0.84
 N018 (50.0)21 (47.8)
Radiotherapy
 Yes20 (56.6)37 (84.1)0.005
 No16 (44.4)7 (15.9)
Chemotherapy
 Yes19 (52.8)33 (75.0)0.038
 No17 (47.2)11 (25.0)
Endocrine therapy
 Yes19 (52.8)23 (52.3)0.96
 No17 (47.2)21 (47.7)
Side CPM
 Right23 (63.9)21 (47.7)0.30
 Left13 (36.1)21 (52.3)
Reconstruction with
 Permanent implant15 (41.7)12 (27.3)0.18
 Expandable implant21 (58.3)32 (72.7)
Simultaneous operation on cancer side
 Delayed reconstruction16 (44.4)16 (36.4)0.59
 Completion mastectomy with IBR12 (33.4)20 (45.5)
 Implant replacement4 (11.1)4 (9.1)
 No operation4 (11.1)4 (9.1)

CRRM: contralateral prophylactic mastectomy; IBR: immediate breast reconstruction.
#Unanticipated surgical procedure on any breast after CRRM with breast reconstruction.
Fisher’s exact test.
Removal of the remaining breast after previous breast-conservative surgery.
Patient screened negative for known mutations having any other case of BC onset before the age of 50 in the family.
Five participants underwent prophylactic salpingo-oophorectomy after CPM.
One patient underwent therapeutic mastectomy.