Clinical Study

Association of One-Step Nucleic Acid Amplification Detected Micrometastases with Tumour Biology and Adjuvant Chemotherapy

Table 2

Tumour characteristics of patients who underwent adjuvant chemotherapy.

Pre-OSNAPost-OSNA
(2009–2012)(2013)

Number of patients (n/%)2123
Age (range)54 (39–69)53 (32–74)
Screen detected6 (28.5%)6 (26%)
Tumour size (mm)26.521.8
Tumour grade (n/%)
 Grade 11 (5%)0 (0%)
 Grade 212 (57%)7 (30%)
 Grade 38 (38%)16 (70%)
ER receptor (n/%)
 Positive17 (80.9%)14 (60.8%)
 Negative4 (19.1%)8 (38%)
 Borderline01 (1.2%)
HER-2 receptor (n/%)
 Positive2 (9.5%)6 (25.1%)
 Negative19 (90.5%)17 (73.9%)
Triple negative (n/%)4 (19%)6 (26%)
Predicted 10-year survival benefit with chemotherapy >3%11 (52%)16 (70%)