Resurrecting Brinley Plots for a Novel Use: Meta-Analyses of Functional Brain Imaging Data in Older Adults
Figure 1
Representative voxel illustrating testing of the
null hypothesis (H0 : ).
To assess whether the null hypothesis is true in any given voxel,
a t-test
comparison of the residual
values was used. When ,
then the line was not significantly close to one and
the voxel was considered
to have a significant deviant slope. If the
value survived the correction for
multiple comparison (3 contiguous voxels where FWE < .05),
the respective
brain area was considered to be a loci for
general cognitive slowing. A second
analysis is needed to identify areas where
voxels with slopes of −1 were
eliminated in the residual analysis.
