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International Journal of Biomedical Imaging
Volume 2008, Article ID 274164, 8 pages
Research Article

MMSE Reconstruction for 3D Freehand Ultrasound Imaging

1Department of Electrical and Computer Engineering, University of Virginia, Charlottesville, VA 22904, USA
2GE Healthcare, 3000 N Grandview Blvd, Waukesha, WI, 53188, USA

Received 10 November 2007; Accepted 27 January 2008

Academic Editor: Guowei Wei

Copyright © 2008 Wei Huang and Yibin Zheng. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


The reconstruction of 3D ultrasound (US) images from mechanically registered, but otherwise irregularly positioned, B-scan slices is of great interest in image guided therapy procedures. Conventional 3D ultrasound algorithms have low computational complexity, but the reconstructed volume suffers from severe speckle contamination. Furthermore, the current method cannot reconstruct uniform high-resolution data from several low-resolution B-scans. In this paper, the minimum mean-squared error (MMSE) method is applied to 3D ultrasound reconstruction. Data redundancies due to overlapping samples as well as correlation of the target and speckle are naturally accounted for in the MMSE reconstruction algorithm. Thus, the reconstruction process unifies the interpolation and spatial compounding. Simulation results for synthetic US images are presented to demonstrate the excellent reconstruction.