Statistical Evaluations of the Reproducibility and Reliability of 3-Tesla High Resolution Magnetization Transfer Brain Images: A Pilot Study on Healthy Subjects

Table 1

The random or fixed effects in the data structure for the repeated measures MT study.

Outcome Variable 𝑌𝑖𝑗𝑘𝑙𝑛	Effect in the Variance-Component Analysis	Type of Effect	Mathematical Symbol	Index	Maximum of the Index
Mean ROI Value via Manual Segmentations	Subject	Random	𝑆𝑖	𝑖=𝑖,…,𝐼	𝐼=9
	Observer	Fixed or Random	𝑂𝑗	𝑗=1,…,𝐽	𝐽=2
	Time Point	Fixed or Random	𝑇𝑘	𝑘=1,…,𝐾	𝐾=2
	Repetition	Fixed or Random	𝑅𝑙	𝑙=1,…,𝐿	𝐿=2
	Region of Interest	Fixed	𝐾𝑚	𝑚=1,…,𝑀	𝑀=12
	Interaction Terms	Generally Mixed	{𝑆𝑖;𝑂𝑗;𝑇𝑘;𝑅𝑙;𝐾𝑚}	{𝑖;𝑗;𝑘;𝑙;𝑛}	Based on the Appropriate Model Specification