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International Journal of Biomedical Imaging
Volume 2010, Article ID 913434, 9 pages
Research Article

Study on Photon Transport Problem Based on the Platform of Molecular Optical Simulation Environment

1School of Electronic Engineering, Xidian University, Xi'an, Shaanxi 710071, China
2Life Sciences Research Center, School of Life Sciences and Technology, Xidian University, Xi'an, Shaanxi 710071, China
3Institute of Automation, Chinese Academy of Sciences, Beijing 100190, China

Received 30 September 2009; Revised 18 December 2009; Accepted 5 February 2010

Academic Editor: Shan Zhao

Copyright © 2010 Kuan Peng et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


As an important molecular imaging modality, optical imaging has attracted increasing attention in the recent years. Since the physical experiment is usually complicated and expensive, research methods based on simulation platforms have obtained extensive attention. We developed a simulation platform named Molecular Optical Simulation Environment (MOSE) to simulate photon transport in both biological tissues and free space for optical imaging based on noncontact measurement. In this platform, Monte Carlo (MC) method and the hybrid radiosity-radiance theorem are used to simulate photon transport in biological tissues and free space, respectively, so both contact and noncontact measurement modes of optical imaging can be simulated properly. In addition, a parallelization strategy for MC method is employed to improve the computational efficiency. In this paper, we study the photon transport problems in both biological tissues and free space using MOSE. The results are compared with , simplified spherical harmonics method (), and physical measurement to verify the performance of our study method on both accuracy and efficiency.