Landmark Optimization Using Local Curvature for Point-Based Nonlinear Rodent Brain Image Registration

Table 1

Pseudocode of the landmark generation and optimization technique.

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(1) Identify homologous contours on the source and target images either by manually drawing or using image processing techniques.

(2) Split the homologous contours into C pairs of corresponding source and target curves.

(3) For c = 1 to C

   For i = 3 to n

     Add the ith landmark on the middle of the longest segment of the cth source curve and the homologous landmark on the corresponding target segment.

     Optimize landmarks by minimizing the cost function in (1).

   End

(4) End

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