Quantification of Lung Damage in an Elastase-Induced Mouse Model of Emphysema

Table 6

Optimal estimated parameters, best features and corresponding area under the ROC curve (AUC), and 𝑓₁-score for each classifier (trained on micro-CT density-based descriptors, RNA cytokine expression data, and single compartment model parameters from pulmonary function tests (PFTs)) are shown.

Classifier	Optimal parameter	Features	AUC	𝑓1-score
Micro-CT	Υ=10^−4;𝑃=10^8	MLI, VBT, RMBR	0.95	0.92
Cytokine	Υ=10^−2;𝑃=10^5	KC, IL6, IP10	0.88	0.71
PFTs	Υ=10^−6;𝑃=10^8	R	0.71	0.66