The Smoothing Artifact of Spatially Constrained Canonical Correlation Analysis in Functional MRI
Motor activation maps for contrast “motor” minus “fixation” using different data analysis methods (single voxel with Gaussian smoothing (GS), CCA with the sum constraint (cCCA sum), CCA with the average constraint (cCCA avg), CCA with the maximum constraint (cCCA max)). In (a), original activations maps are shown at FWE <0.05. In (b), activation maps corrected for the smoothing artifact are shown. Corrections are done for . In (c), voxels affected by the smoothing artifact are shown. The color scale on the right refers to the magnitude of the smoothing artifact in (c). In (d) we show for comparison the activation map for single voxel analysis without Gaussian smoothing.
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